STRINGSTRING
topA protein (Thermoproteus tenax) - STRING interaction network
"topA" - Topoisomerase in Thermoproteus tenax
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
topATopoisomerase (DNA) III alpha (606 aa)    
Predicted Functional Partners:
rfc
Replication factor C small subunit (321 aa)
 
  0.933
TTX_1160
RadA-like protein (310 aa)
 
  0.924
rpoD
DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (281 aa)
 
 
  0.923
rfcS
Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA (328 aa)
 
  0.921
TTX_1917
DNA polymerase II (785 aa)
   
  0.914
polB2
Possible DNA-directed DNA polymerase (550 aa)
   
  0.914
TTX_0168
polB DNA-directed DNA polymerase I (B1) (860 aa)
   
  0.914
rfcL
Replication factor C, large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA (423 aa)
   
  0.913
radA
DNA repair protein; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (382 aa)
 
  0.912
rpoA1
DNA-directed RNA polymerase subunit A’; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (883 aa)
   
 
  0.906
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax, T. tenax Kra 1, Thermoproteus tenax, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
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