STRINGSTRING
pfpI protein (Thermoproteus tenax) - STRING interaction network
"pfpI" - Intracellular protease/amidase in Thermoproteus tenax
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfpIIntracellular protease/amidase (181 aa)    
Predicted Functional Partners:
ahpC
Alkyl hydroperoxide reductase (212 aa)
   
 
  0.902
egsA
Glycerol-1-phosphate dehydrogenase GLPDH; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea (344 aa)
   
        0.884
adkA
Adenylate kinase (197 aa)
 
          0.843
pknA2
Serine/threonine protein kinase (498 aa)
     
 
  0.839
rpl2
50S ribosomal protein L2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (243 aa)
   
      0.806
rps10
Ribosomal protein S10p; Involved in the binding of tRNA to the ribosomes (106 aa)
   
      0.804
rps3
30S ribosomal protein S3p; Binds the lower part of the 30S subunit head (216 aa)
     
      0.802
rpl
50S ribosomal protein L14p; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (148 aa)
     
      0.793
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP (510 aa)
   
   
  0.758
rpl5
50S ribosomal protein L5p; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (184 aa)
     
 
  0.750
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax, T. tenax Kra 1, Thermoproteus tenax, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
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