STRINGSTRING
eif6 protein (Thermoproteus tenax) - STRING interaction network
"eif6" - Translation initiation factor eIF-6 in Thermoproteus tenax
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eif6Translation initiation factor eIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex (221 aa)    
Predicted Functional Partners:
rpl10
50S ribosomal protein L10e; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors (346 aa)
 
 
  0.985
rplX
Putative 50S ribosomal protein LXa (83 aa)
   
 
  0.984
rpl15e
50S ribosomal protein L15e (184 aa)
   
 
  0.981
fusA
Elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (740 aa)
     
 
  0.978
rpl24e
Putative 50S ribosomal protein L24e; Binds to the 23S rRNA (63 aa)
   
 
  0.978
rpl3
50S ribosomal protein L3p; One of the primary rRNA binding proteins, it binds directly near the 3’-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (339 aa)
   
 
  0.977
flpA
Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2’-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (235 aa)
   
 
  0.974
rpl7ae
50S ribosomal protein L7ae; Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C’/D’ sRNAs (150 aa)
 
 
  0.973
rpl18
50S ribosomal protein L18p; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (203 aa)
   
 
  0.972
rpl32e
Putative 50S ribosomal protein L32e (162 aa)
   
 
  0.969
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax, T. tenax Kra 1, Thermoproteus tenax, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
Server load: low (8%) [HD]