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hflX protein (Thermoproteus tenax) - STRING interaction network
"hflX" - GTP-binding protein HflX in Thermoproteus tenax
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
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Experiments
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[Homology]
Score
hflXGTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (399 aa)    
Predicted Functional Partners:
mbf1
Multprotein bridging factor (157 aa)
              0.898
tfe
Transcription initiation factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation comple [...] (178 aa)
              0.898
TTX_1935
ATP-grasp superfamily enzyme (234 aa)
              0.898
rpl
50S ribosomal protein L14p; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (148 aa)
 
 
 
  0.896
rpl1
50S ribosomal protein L1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release (223 aa)
   
 
  0.891
rpl5
50S ribosomal protein L5p; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (184 aa)
   
 
  0.891
rpl10
50S ribosomal protein L10e; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors (346 aa)
   
 
  0.889
rpl2
50S ribosomal protein L2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (243 aa)
   
 
  0.888
rpl24p
50S ribosomal protein L24p; Located at the polypeptide exit tunnel on the outside of the subunit (126 aa)
   
 
  0.886
rpl23p
50S ribosomal protein L23p; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome (83 aa)
     
 
  0.884
Your Current Organism:
Thermoproteus tenax
NCBI taxonomy Id: 768679
Other names: T. tenax, T. tenax Kra 1, Thermoproteus tenax, Thermoproteus tenax DSM 2078, Thermoproteus tenax JCM 9277, Thermoproteus tenax Kra 1, Thermoproteus tenax str. Kra 1, Thermoproteus tenax strain Kra 1
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