STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1W2TRX13-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (273 aa)    
Predicted Functional Partners:
A0A1W2TPU7
Putative pantoate-beta-alanine ligase.
 
 0.999
A0A1W2TLV9
Putative 2-dehydropantoate 2-reductase.
     
 0.844
A0A1S8A6P3
Putative dihydroxy-acid dehydratase.
     
 0.830
A0A1W2TCF1
Putative dihydroxy-acid dehydratase.
     
 0.830
A0A1W2TAE9
Putative dihydroxy-acid dehydratase.
     
 0.829
A0A1W2TKV8
Putative dihydroxy-acid dehydratase.
     
 0.829
A0A1W2TGR5
Putative branched-chain-amino-acid aminotransferase 1.
    
 0.828
A0A1W2TJA6
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.828
A0A1W2TME9
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.828
A0A1W2TJF3
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
    
 0.815
Your Current Organism:
Rosellinia necatrix
NCBI taxonomy Id: 77044
Other names: R. necatrix
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