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FEN1 protein (Sordaria macrospora) - STRING interaction network
"FEN1" - Hypothetical protein in Sordaria macrospora
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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FEN1Hypothetical protein; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] (394 aa)    
Predicted Functional Partners:
SMAC_04881
Hypothetical protein; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (259 aa)
     
  0.996
SMAC_03669
MSH2 protein; Component of the post-replicative DNA mismatch repair system (MMR) (934 aa)
   
  0.976
SMAC_04895
SGS1 protein (2276 aa)
   
  0.967
SMAC_00050
MRE11 protein (718 aa)
   
  0.950
SMAC_03385
Hypothetical protein (1750 aa)
   
  0.948
SMAC_04344
Hypothetical protein (387 aa)
   
  0.943
SMAC_06760
Hypothetical protein (352 aa)
   
  0.918
SMAC_05315
Hypothetical protein (934 aa)
   
  0.912
SMAC_06758
Hypothetical protein (1075 aa)
   
  0.908
SMAC_07160
Hypothetical protein (971 aa)
   
 
  0.898
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 771870
Other names: S. macrospora, S. macrospora k-hell, Sordaria, Sordaria macrospora, Sordaria macrospora k hell, Sordaria macrospora k-hell
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