STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAC_07534WGS project CABT00000000 data, contig 2.7. (1314 aa)    
Predicted Functional Partners:
SMAC_05004
WGS project CABT00000000 data, contig 2.8.
    
 0.998
SMAC_07055
WGS project CABT00000000 data, contig 2.36.
    
 0.998
SMAC_02965
WGS project CABT00000000 data, contig 2.12.
    
 0.994
SMAC_00414
WGS project CABT00000000 data, contig 2.1.
    
 0.987
SMAC_02159
WGS project CABT00000000 data, contig 2.18.
    
 0.984
SMAC_06682
WGS project CABT00000000 data, contig 2.13; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
   
0.975
SMAC_00083
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.
   
 0.974
SMAC_01813
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.962
SMAC_08815
WGS project CABT00000000 data, contig 2.66.
     
 0.959
SMAC_00488
WGS project CABT00000000 data, contig 2.1.
    
 0.953
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.