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GET3 protein (Sordaria macrospora) - STRING interaction network
"GET3" - Hypothetical protein in Sordaria macrospora
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
GET3Hypothetical protein; ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] (334 aa)    
Predicted Functional Partners:
GET1
Hypothetical protein; Required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol (214 aa)
       
  0.971
SMAC_07550
Hypothetical protein (342 aa)
       
 
  0.950
SMAC_02014
Hypothetical protein (84 aa)
       
 
  0.725
SMAC_02013
RAD23 protein (249 aa)
       
 
  0.725
SMAC_05120
Hypothetical protein (476 aa)
     
  0.696
SMAC_06810
Hypothetical protein (317 aa)
       
 
  0.642
SMAC_03770
Hypothetical protein (381 aa)
     
 
  0.601
SMAC_01015
Hypothetical protein (416 aa)
     
  0.548
SMAC_02255
Hypothetical protein (700 aa)
       
    0.536
SMAC_06967
Hypothetical protein; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (251 aa)
     
      0.521
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 771870
Other names: S. macrospora, S. macrospora k-hell, Sordaria, Sordaria macrospora, Sordaria macrospora k hell, Sordaria macrospora k-hell
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