STRINGSTRING
SMAC_04096 protein (Sordaria macrospora) - STRING interaction network
"SMAC_04096" - Hypothetical protein in Sordaria macrospora
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAC_04096Hypothetical protein (463 aa)    
Predicted Functional Partners:
SMAC_01010
TOP2 protein (1915 aa)
   
  0.946
SMAC_00168
TOP3 protein; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (603 aa)
   
  0.871
SMAC_11496
Hypothetical protein (116 aa)
   
  0.871
SMAC_06758
Hypothetical protein (1075 aa)
     
  0.826
SMAC_03113
RFA1 protein (610 aa)
     
  0.820
SMAC_04277
RAD51 protein (353 aa)
     
  0.820
FEN1
Hypothetical protein; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] (394 aa)
   
  0.815
SMAC_00927
Hypothetical protein (646 aa)
     
  0.812
SMAC_04895
SGS1 protein (2276 aa)
         
0.811
SMAC_00050
MRE11 protein (718 aa)
   
  0.811
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 771870
Other names: S. macrospora, S. macrospora k-hell, Sordaria, Sordaria macrospora, Sordaria macrospora k hell, Sordaria macrospora k-hell
Server load: low (7%) [HD]