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SMAC_00910 protein (Sordaria macrospora) - STRING interaction network
"SMAC_00910" - MLH1 protein in Sordaria macrospora
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAC_00910MLH1 protein (752 aa)    
Predicted Functional Partners:
SMAC_01858
Hypothetical protein (1251 aa)
     
0.975
SMAC_03669
MSH2 protein; Component of the post-replicative DNA mismatch repair system (MMR) (934 aa)
 
  0.964
SMAC_03612
MSH6 protein; Component of the post-replicative DNA mismatch repair system (MMR) (1230 aa)
 
  0.961
SMAC_08039
MSH3 protein; Component of the post-replicative DNA mismatch repair system (MMR) (1157 aa)
 
  0.960
SMAC_06425
EXO1 protein (722 aa)
     
  0.947
SMAC_01471
MSH4 protein (1242 aa)
   
  0.905
SMAC_04248
MSH5 protein (923 aa)
   
  0.905
FEN1
Hypothetical protein; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] (394 aa)
     
  0.890
SMAC_06758
Hypothetical protein (1075 aa)
   
 
  0.884
SMAC_00355
Hypothetical protein (1299 aa)
   
  0.869
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 771870
Other names: S. macrospora, S. macrospora k-hell, Sordaria, Sordaria macrospora, Sordaria macrospora k hell, Sordaria macrospora k-hell
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