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MDM12 protein (Sordaria macrospora) - STRING interaction network
"MDM12" - Hypothetical protein in Sordaria macrospora
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
MDM12Hypothetical protein; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane [...] (645 aa)    
Predicted Functional Partners:
MMM1
Hypothetical protein; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of t [...] (415 aa)
     
  0.964
MDM10
Hypothetical protein; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. [...] (476 aa)
       
  0.956
MDM34
Hypothetical protein; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10 (583 aa)
       
  0.953
SMAC_08468
Dynamin-related protein (802 aa)
         
  0.855
SMAC_04485
Hypothetical protein (707 aa)
         
  0.853
SMAC_06135
Hypothetical protein; Mitochondrial GTPase involved in mitochondrial trafficking (629 aa)
       
  0.767
SMAC_07561
Hypothetical protein (349 aa)
         
  0.680
SMAC_03302
Hypothetical protein (513 aa)
         
  0.667
SMAC_07824
Hypothetical protein (624 aa)
       
  0.658
SMAC_01870
Hypothetical protein (155 aa)
         
  0.652
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 771870
Other names: S. macrospora, S. macrospora k-hell, Sordaria, Sordaria macrospora, Sordaria macrospora k hell, Sordaria macrospora k-hell
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