STRINGSTRING
ssrp1 protein (Ciona intestinalis) - STRING interaction network
"ssrp1" - FACT complex subunit SSRP1 in Ciona intestinalis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ssrp1FACT complex subunit SSRP1 ; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment [...] (603 aa)    
Predicted Functional Partners:
supt16h
Uncharacterized protein (1035 aa)
     
  0.995
ENSCING00000008994
Uncharacterized protein (1034 aa)
     
  0.983
LOC494392
Uncharacterized protein LOC494392 (131 aa)
     
  0.980
ENSCING00000015908
Uncharacterized protein (166 aa)
     
  0.978
ck2a
Casein kinase 2 alpha subunit (385 aa)
     
  0.973
ENSCING00000006333
Uncharacterized protein (336 aa)
     
  0.973
ck2b
Protein kinase Ck2-beta ; Plays a complex role in regulating the basal catalytic activity of the alpha subunit (215 aa)
     
  0.972
ENSCING00000018637
Uncharacterized protein (189 aa)
     
  0.964
ci-htf-1
Transcription factor ; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1297 aa)
     
 
  0.962
ENSCING00000001161
Uncharacterized protein ; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (121 aa)
       
  0.933
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: C. intestinalis, Ciona intestinalis
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