STRINGSTRING
smoothened protein (Ciona intestinalis) - STRING interaction network
"smoothened" - Smoothened protein in Ciona intestinalis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smoothenedSmoothened protein (441 aa)    
Predicted Functional Partners:
ENSCING00000018399
Uncharacterized protein (1179 aa)
     
  0.939
gli
Transcription factor protein (1098 aa)
     
  0.867
hh2
Hedgehog homolog 2 precursor (312 aa)
     
 
  0.852
hh1
Hedgehog homolog 1 ; Intercellular signal essential for a variety of patterning events during development (557 aa)
     
 
  0.850
wnt3
Wingless-type MMTV integration site family, member 3 ; Ligand for members of the frizzled family of seven transmembrane receptors (304 aa)
       
  0.844
ENSCING00000008083
Uncharacterized protein (473 aa)
     
 
  0.826
ENSCING00000006822
Protein Wnt ; Ligand for members of the frizzled family of seven transmembrane receptors (175 aa)
       
  0.809
wnt5
Wnt signaling ligand precursor ; Ligand for members of the frizzled family of seven transmembrane receptors (360 aa)
     
  0.795
LOC778722
Protein Wnt ; Ligand for members of the frizzled family of seven transmembrane receptors (190 aa)
       
  0.795
wnt7
Protein Wnt ; Ligand for members of the frizzled family of seven transmembrane receptors (369 aa)
       
  0.795
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: C. intestinalis, Ciona intestinalis
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