STRINGSTRING
zf(parp)-2 protein (Ciona intestinalis) - STRING interaction network
"zf(parp)-2" - DNA ligase in Ciona intestinalis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zf(parp)-2DNA ligase (859 aa)    
Predicted Functional Partners:
ENSCING00000014118
Proliferating cell nuclear antigen ; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (262 aa)
     
  0.958
pold1
DNA polymerase (1064 aa)
     
  0.883
ENSCING00000009655
DNA polymerase (2157 aa)
     
  0.847
ENSCING00000007673
Uncharacterized protein (217 aa)
     
  0.845
ENSCING00000001608
DNA polymerase (382 aa)
     
  0.840
ENSCING00000002409
Uncharacterized protein ; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts [...] (380 aa)
   
  0.813
ENSCING00000020135
Uncharacterized protein (480 aa)
     
  0.813
ENSCING00000004516
Zinc finger protein ZF(C2H2)-102 ; Single-stranded DNA-dependent ATP-dependent helicase (706 aa)
     
  0.809
ENSCING00000017214
Uncharacterized protein (276 aa)
     
  0.787
ENSCING00000022190
Uncharacterized protein (326 aa)
   
  0.786
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: C. intestinalis, Ciona intestinalis
Server load: low (7%) [HD]