STRINGSTRING
PIF1 protein (Ciona intestinalis) - STRING interaction network
"PIF1" - Uncharacterized protein in Ciona intestinalis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIF1Uncharacterized protein ; DNA-dependent ATPase and 5’-3’ DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability (607 aa)    
Predicted Functional Partners:
ENSCING00000002042
Uncharacterized protein (1111 aa)
     
 
  0.858
ENSCING00000014118
Proliferating cell nuclear antigen ; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (262 aa)
   
 
  0.835
Cin.49685
Uncharacterized protein (265 aa)
   
 
  0.812
ENSCING00000005560
Uncharacterized protein (983 aa)
   
 
  0.808
ENSCING00000019579
Uncharacterized protein (328 aa)
   
 
  0.693
ENSCING00000003315
Uncharacterized protein (432 aa)
     
 
  0.689
ENSCING00000021163
Uncharacterized protein ; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (179 aa)
     
 
  0.661
top3b
DNA topoisomerase ; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (820 aa)
     
 
  0.661
top3a
DNA topoisomerase ; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (456 aa)
     
 
  0.661
ENSCING00000001582
Uncharacterized protein (553 aa)
     
 
  0.641
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: C. intestinalis, Ciona intestinalis
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