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pkm protein (Ciona intestinalis) - STRING interaction network
"pkm" - Pyruvate kinase in Ciona intestinalis
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pkmPyruvate kinase (534 aa)    
Predicted Functional Partners:
ENSCING00000007313
Uncharacterized protein (440 aa)
   
  0.999
ENSCING00000002238
Phosphoglycerate kinase (416 aa)
   
  0.991
ENSCING00000011997
Triosephosphate isomerase (247 aa)
   
 
  0.987
ENSCING00000003426
L-lactate dehydrogenase (341 aa)
   
  0.977
pc
Pyruvate carboxylase ; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (1186 aa)
     
  0.972
ENSCING00000003848
Uncharacterized protein ; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways (230 aa)
   
 
  0.970
ENSCING00000010459
Uncharacterized protein ; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (385 aa)
   
 
  0.969
ENSCING00000009446
Glucose-6-phosphate isomerase (232 aa)
   
   
  0.966
ENSCING00000017302
Fructose-bisphosphate aldolase (364 aa)
   
  0.966
akd1
Uncharacterized protein (1861 aa)
   
 
  0.964
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: C. intestinalis, Ciona intestinalis
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