Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein (248 aa)
Predicted Functional Partners:
Notch precursor (2549 aa)
Glycogen synthase kinase alpha/beta (407 aa)
Suppressor of hairless homolog ; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes (By similarity). Required for the transcriptional expression of Brachyury, suggesting that it participates in notochord differentiation (554 aa)
Uncharacterized protein (475 aa)
Uncharacterized protein (162 aa)
Beta-transducin repeat-containing homologue protein (621 aa)
Uncharacterized protein (773 aa)
Groucho (835 aa)
Groucho (847 aa)
Janus kinase (1138 aa)
Your Current Organism:
NCBI taxonomy Id: 7719 Other names: C. intestinalis, Ciona intestinalis