STRINGSTRING
cir protein (Ciona intestinalis) - STRING interaction network
"cir" - CIR protein in Ciona intestinalis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cirCIR protein (242 aa)    
Predicted Functional Partners:
su(h)
Suppressor of hairless homolog ; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes (By similarity). Required for the transcriptional expression of Brachyury, suggesting that it participates in notochord differentiation (554 aa)
       
  0.901
Cin.52569
Histone deacetylase (404 aa)
     
  0.844
ENSCING00000004186
Uncharacterized protein (475 aa)
       
 
  0.527
ENSCING00000008595
Zinc finger protein (CCHC)-12 (568 aa)
     
        0.410
ENSCING00000009048
Uncharacterized protein (802 aa)
     
        0.402
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: C. intestinalis, Ciona intestinalis
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