STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIS1_BRAFLLissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes. (406 aa)    
Predicted Functional Partners:
C3Y0T9_BRAFL
Uncharacterized protein.
    
 0.973
C3Z6R3_BRAFL
NUDE_C domain-containing protein.
    
 
 0.963
C3ZLJ1_BRAFL
CS domain-containing protein.
   
 0.940
C3YA29_BRAFL
WD_REPEATS_REGION domain-containing protein.
   
 0.933
C3ZHP4_BRAFL
Uncharacterized protein.
    
 0.930
C3YN11_BRAFL
Uncharacterized protein.
     
 0.924
C3XTW3_BRAFL
Uncharacterized protein.
     
  0.900
C3ZZ86_BRAFL
Uncharacterized protein.
     
  0.900
C3ZWS4_BRAFL
PLA2c domain-containing protein.
     
  0.861
C3XTX4_BRAFL
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
   
 0.803
Your Current Organism:
Branchiostoma floridae
NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet
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