node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Xaut_1881 | Xaut_3282 | Xaut_1881 | Xaut_3282 | PFAM: protein of unknown function DUF107; KEGG: nwi:Nwi_0930 protein of unknown function DUF107. | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rle:pRL110628 precorrin-3b c(17)-methyltransferase (precorrin-3 methyltransferase) (precorrin-3 methylase). | 0.402 |
Xaut_1881 | cobS | Xaut_1881 | Xaut_4260 | PFAM: protein of unknown function DUF107; KEGG: nwi:Nwi_0930 protein of unknown function DUF107. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.766 |
Xaut_2161 | Xaut_3776 | Xaut_2161 | Xaut_3776 | TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: nwi:Nwi_0752 cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.927 |
Xaut_2161 | Xaut_3777 | Xaut_2161 | Xaut_3777 | TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: nwi:Nwi_0752 cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.939 |
Xaut_2161 | cobB | Xaut_2161 | Xaut_3276 | TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: nwi:Nwi_0752 cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.920 |
Xaut_2161 | cobD | Xaut_2161 | Xaut_3779 | TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: nwi:Nwi_0752 cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.920 |
Xaut_2161 | cobQ | Xaut_2161 | Xaut_3778 | TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: nwi:Nwi_0752 cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.924 |
Xaut_2161 | cobS | Xaut_2161 | Xaut_4260 | TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: nwi:Nwi_0752 cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.929 |
Xaut_3278 | Xaut_3282 | Xaut_3278 | Xaut_3282 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sme:SMc03187 probable precorrin-4 C11-methyltransferase protein; Belongs to the precorrin methyltransferase family. | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rle:pRL110628 precorrin-3b c(17)-methyltransferase (precorrin-3 methyltransferase) (precorrin-3 methylase). | 0.999 |
Xaut_3278 | Xaut_3776 | Xaut_3278 | Xaut_3776 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sme:SMc03187 probable precorrin-4 C11-methyltransferase protein; Belongs to the precorrin methyltransferase family. | Adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.898 |
Xaut_3278 | Xaut_3777 | Xaut_3278 | Xaut_3777 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sme:SMc03187 probable precorrin-4 C11-methyltransferase protein; Belongs to the precorrin methyltransferase family. | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.559 |
Xaut_3278 | cobB | Xaut_3278 | Xaut_3276 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sme:SMc03187 probable precorrin-4 C11-methyltransferase protein; Belongs to the precorrin methyltransferase family. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.907 |
Xaut_3278 | cobD | Xaut_3278 | Xaut_3779 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sme:SMc03187 probable precorrin-4 C11-methyltransferase protein; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.861 |
Xaut_3278 | cobQ | Xaut_3278 | Xaut_3778 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sme:SMc03187 probable precorrin-4 C11-methyltransferase protein; Belongs to the precorrin methyltransferase family. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.958 |
Xaut_3278 | cobS | Xaut_3278 | Xaut_4260 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sme:SMc03187 probable precorrin-4 C11-methyltransferase protein; Belongs to the precorrin methyltransferase family. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.794 |
Xaut_3278 | cobT | Xaut_3278 | Xaut_3321 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sme:SMc03187 probable precorrin-4 C11-methyltransferase protein; Belongs to the precorrin methyltransferase family. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.715 |
Xaut_3282 | Xaut_1881 | Xaut_3282 | Xaut_1881 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rle:pRL110628 precorrin-3b c(17)-methyltransferase (precorrin-3 methyltransferase) (precorrin-3 methylase). | PFAM: protein of unknown function DUF107; KEGG: nwi:Nwi_0930 protein of unknown function DUF107. | 0.402 |
Xaut_3282 | Xaut_3278 | Xaut_3282 | Xaut_3278 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rle:pRL110628 precorrin-3b c(17)-methyltransferase (precorrin-3 methyltransferase) (precorrin-3 methylase). | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sme:SMc03187 probable precorrin-4 C11-methyltransferase protein; Belongs to the precorrin methyltransferase family. | 0.999 |
Xaut_3282 | Xaut_3776 | Xaut_3282 | Xaut_3776 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rle:pRL110628 precorrin-3b c(17)-methyltransferase (precorrin-3 methyltransferase) (precorrin-3 methylase). | Adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.599 |
Xaut_3282 | Xaut_3777 | Xaut_3282 | Xaut_3777 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rle:pRL110628 precorrin-3b c(17)-methyltransferase (precorrin-3 methyltransferase) (precorrin-3 methylase). | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.464 |