STRINGSTRING
TSC2 protein (Latimeria chalumnae) - STRING interaction network
"TSC2" - Tuberous sclerosis 2 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSC2Tuberous sclerosis 2 (1836 aa)    
Predicted Functional Partners:
TSC1
Tuberous sclerosis 1 (1217 aa)
     
  0.997
RHEB
Ras homolog enriched in brain (184 aa)
     
  0.993
RHEBL1
Ras homolog enriched in brain like 1 (184 aa)
     
  0.990
AKT3
V-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) (470 aa)
     
  0.977
AKT1
V-akt murine thymoma viral oncogene homolog 1 (478 aa)
     
  0.977
PRKAA1
Protein kinase, AMP-activated, alpha 1 catalytic subunit (552 aa)
     
  0.964
PRKAA2
Protein kinase, AMP-activated, alpha 2 catalytic subunit (553 aa)
     
  0.963
RPS6KA2
Ribosomal protein S6 kinase, 90kDa, polypeptide 2 (740 aa)
     
  0.960
RPS6KA6
Ribosomal protein S6 kinase, 90kDa, polypeptide 6 (726 aa)
     
  0.960
RPS6KA1
Ribosomal protein S6 kinase, 90kDa, polypeptide 1 (712 aa)
     
  0.960
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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