STRINGSTRING
TSC2 protein (Latimeria chalumnae) - STRING interaction network
"TSC2" - Tuberous sclerosis 2 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSC2Tuberous sclerosis 2 (1836 aa)    
Predicted Functional Partners:
RHEB
Ras homolog enriched in brain (184 aa)
     
  0.997
RHEBL1
Ras homolog enriched in brain like 1 (184 aa)
     
  0.994
TBC1D7
TBC1 domain family, member 7 (293 aa)
       
  0.990
TSC1
Tuberous sclerosis 1a (1217 aa)
     
 
  0.983
RPS6KA1
Ribosomal protein S6 kinase, 90kDa, polypeptide 1 (712 aa)
     
  0.961
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily (420 aa)
     
  0.960
DDIT4
DNA-damage-inducible transcript 4 (222 aa)
         
  0.954
AKT1
V-akt murine thymoma viral oncogene homolog 1 (478 aa)
     
  0.950
AKT3
V-akt murine thymoma viral oncogene homolog 3 (470 aa)
     
  0.940
RPS6KA2
Ribosomal protein S6 kinase, 90kDa, polypeptide 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily (740 aa)
     
  0.935
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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