STRINGSTRING
APPL2 protein (Latimeria chalumnae) - STRING interaction network
"APPL2" - Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APPL2Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (484 aa)    
Predicted Functional Partners:
APPL1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 (709 aa)
     
0.834
RAB5B
RAB5B, member RAS oncogene family (229 aa)
     
  0.804
RAB24
RAB24, member RAS oncogene family (203 aa)
     
  0.804
RAB20
RAB20, member RAS oncogene family (235 aa)
     
  0.804
RAB5C
RAB5C, member RAS oncogene family (216 aa)
     
  0.804
RAB31
RAB31, member RAS oncogene family (195 aa)
     
  0.804
RAB22A
RAB22A, member RAS oncogene family (194 aa)
     
  0.804
ENSLACG00000005991
Uncharacterized protein (213 aa)
     
  0.804
RAB5A
RAB5A, member RAS oncogene family (230 aa)
     
  0.804
CASP7
Caspase 7, apoptosis-related cysteine peptidase (313 aa)
       
  0.650
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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