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TDO2 protein (Latimeria chalumnae) - STRING interaction network
"TDO2" - Tryptophan 2,3-dioxygenase in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TDO2Tryptophan 2,3-dioxygenase (307 aa)    
Predicted Functional Partners:
KYNU
Uncharacterized protein; Kynureninase (278 aa)
 
 
  0.990
AFMID
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites (293 aa)
   
 
  0.979
IDO2
Indoleamine 2,3-dioxygenase 1 (425 aa)
     
 
  0.962
TPH1
Tryptophan hydroxylase 1 (482 aa)
   
 
  0.950
TPH2
Tryptophan hydroxylase 2 (491 aa)
   
 
  0.936
DDC
Dopa decarboxylase (503 aa)
   
 
  0.909
ENSLACG00000004956
Dopa decarboxylase (341 aa)
   
 
  0.909
ENSLACG00000002264
annotation not available (516 aa)
     
 
  0.905
ENSLACG00000000464
annotation not available (519 aa)
     
 
  0.905
KMO
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (474 aa)
 
   
  0.870
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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