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STRINGSTRING
ENSLACG00000000354 protein (Latimeria chalumnae) - STRING interaction network
"ENSLACG00000000354" - Very-long-chain in Latimeria chalumnae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ENSLACG00000000354Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long- chain fatty acids elongation cycle. This endoplasmic reticulum- bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursor [...] (148 aa)    
Predicted Functional Partners:
ENSLACG00000010287
trans-2,3-enoyl-CoA reductase-like 2 (317 aa)
     
  0.984
TECR
Uncharacterized protein; trans-2,3-enoyl-CoA reductase (166 aa)
     
  0.984
HSD17B12
Hydroxysteroid (17-beta) dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family (318 aa)
     
  0.962
ENSLACG00000003040
Hydroxysteroid (20-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family (343 aa)
     
  0.936
PTPLAD1
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long- chain fatty acids elongation cycle. This endoplasmic reticulum- bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursor [...] (359 aa)
     
 
0.826
PTPLA
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long- chain fatty acids elongation cycle. This endoplasmic reticulum- bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursor [...] (265 aa)
         
 
0.800
SEC22A
SEC22 vesicle trafficking protein homolog A (S. cerevisiae); Belongs to the synaptobrevin family (304 aa)
     
   
  0.780
ELOVL5
Elongation of very long chain fatty acids protein; ELOVL fatty acid elongase 5 (219 aa)
     
 
  0.670
ELOVL1
Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22-0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involve [...] (302 aa)
     
 
  0.644
SLC46A2
Solute carrier family 46, member 2 (461 aa)
           
  0.634
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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