STRINGSTRING
ASPM protein (Latimeria chalumnae) - STRING interaction network
"ASPM" - Asp (abnormal spindle) homolog, microcephaly associated in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASPMAsp (abnormal spindle) homolog, microcephaly associated (Drosophila) (2977 aa)    
Predicted Functional Partners:
KIF11
Kinesin family member 11 (1059 aa)
     
   
  0.980
NDC80
NDC80 kinetochore complex component homolog (S. cerevisiae) (661 aa)
     
   
  0.817
NCAPG
non-SMC condensin I complex, subunit G (1067 aa)
     
        0.811
SMC4
Structural maintenance of chromosomes 4 (1297 aa)
     
        0.811
TTK
TTK protein kinase (889 aa)
     
   
  0.809
TOP2A
Topoisomerase (DNA) II alpha 170kDa; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1569 aa)
     
   
  0.808
TOP2B
Topoisomerase (DNA) II beta 180kDa; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1615 aa)
     
   
  0.808
RHBDL3
Rhomboid, veinlet-like 3 (Drosophila) (373 aa)
     
  0.768
ENSLACG00000002496
Uncharacterized protein (1882 aa)
     
  0.768
EFCAB2
EF-hand calcium binding domain 2 (162 aa)
       
  0.755
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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