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GNG12 protein (Latimeria chalumnae) - STRING interaction network
"GNG12" - Guanine nucleotide-binding protein subunit gamma in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (68 aa)    
Predicted Functional Partners:
GNB3
G protein subunit beta 3; Guanine nucleotide binding protein (G protein), beta polypeptide 3 (341 aa)
     
 
  0.947
ENSLACG00000019130
annotation not available (340 aa)
     
 
  0.947
GNB1
G protein subunit beta 2; Guanine nucleotide binding protein (G protein), beta polypeptide 1 (343 aa)
     
 
  0.947
GNA12
Guanine nucleotide binding protein (G protein) alpha 12 (382 aa)
     
  0.907
CHRM4
Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins (510 aa)
     
  0.817
CHRM1
Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins (505 aa)
     
  0.817
FGD3
FYVE, RhoGEF and PH domain containing 3 (695 aa)
         
  0.811
FGD1
FYVE, RhoGEF and PH domain containing 1 (832 aa)
         
  0.811
CHRM2
Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins (475 aa)
     
  0.809
CHRM3
Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins (515 aa)
     
    0.808
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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