STRINGSTRING
IBTK protein (Latimeria chalumnae) - STRING interaction network
"IBTK" - Inhibitor of Bruton agammaglobulinemia tyrosine kinase in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IBTKInhibitor of Bruton agammaglobulinemia tyrosine kinase (185 aa)    
Predicted Functional Partners:
ENSLACG00000009728
Uncharacterized protein (3251 aa)
     
  0.742
ENSLACG00000004309
Uncharacterized protein (347 aa)
     
  0.742
RAN
RAN, member RAS oncogene family; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (147 aa)
     
  0.700
HERC4
HECT and RLD domain containing E3 ubiquitin protein ligase 4 (908 aa)
     
  0.654
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3 (1049 aa)
     
  0.654
ENSLACG00000013055
Uncharacterized protein (253 aa)
 
            0.602
HERC6
Probable E3 ubiquitin-protein ligase HERC6 (629 aa)
     
  0.594
ENSLACG00000001058
Uncharacterized protein (937 aa)
     
  0.594
RANGAP1
Ran GTPase activating protein 1 (615 aa)
     
  0.593
KXD1
Ubiquitin A-52 residue ribosomal protein fusion product 1 (231 aa)
     
  0.573
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
Server load: low (8%) [HD]