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STRINGSTRING
RNF139 protein (Latimeria chalumnae) - STRING interaction network
"RNF139" - Ring finger protein 139 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF139Ring finger protein 139 (661 aa)    
Predicted Functional Partners:
KXD1
annotation not available (231 aa)
       
 
  0.845
UBE2G2
Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family (168 aa)
       
 
  0.833
DERL1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome (254 aa)
     
 
  0.789
MARCH6
Membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase (775 aa)
     
 
  0.789
RNF103
Ring finger protein 103 (678 aa)
     
   
  0.776
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase (882 aa)
       
 
  0.743
FAF2
Fas associated factor family member 2 (445 aa)
     
 
  0.742
DERL2
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome (239 aa)
     
 
  0.726
DERL3
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome (203 aa)
     
 
  0.726
AUP1
Ancient ubiquitous protein 1 (423 aa)
     
 
  0.716
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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