STRINGSTRING
RNF139 protein (Latimeria chalumnae) - STRING interaction network
"RNF139" - Ring finger protein 139 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF139Ring finger protein 139 (661 aa)    
Predicted Functional Partners:
DERL2
Derlin 2; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome (239 aa)
     
  0.912
DERL3
Derlin 3; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome (203 aa)
     
  0.912
OS9
Osteosarcoma amplified 9, endoplasmic reticulum lectin (662 aa)
     
  0.908
UBE2G2
Ubiquitin-conjugating enzyme E2G 2 (168 aa)
       
 
  0.890
SEL1L
Sel-1 suppressor of lin-12-like (C. elegans) (759 aa)
     
  0.883
DERL1
Derlin 1; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome (254 aa)
     
  0.869
ERLEC1
Endoplasmic reticulum lectin 1 (486 aa)
     
  0.865
SPATA5L1
Spermatogenesis associated 5-like 1 (792 aa)
     
  0.851
SPATA5
Spermatogenesis associated 5 (795 aa)
     
  0.851
ENSLACG00000015950
Uncharacterized protein (697 aa)
     
  0.851
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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