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LIPA protein (Latimeria chalumnae) - STRING interaction network
"LIPA" - Lipase A, lysosomal acid, cholesterol esterase in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIPALipase A, lysosomal acid, cholesterol esterase; Belongs to the AB hydrolase superfamily. Lipase family (398 aa)    
Predicted Functional Partners:
DHCR7
7-dehydrocholesterol reductase (478 aa)
     
  0.920
CH25H
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family (284 aa)
     
  0.908
DHCR24
24-dehydrocholesterol reductase (516 aa)
     
 
  0.903
CEL
Carboxylic ester hydrolase; Carboxyl ester lipase, tandem duplicate 1; Belongs to the type-B carboxylesterase/lipase family (552 aa)
     
 
  0.876
ENSLACG00000014896
Cholesterol 25-hydroxylase like 1, tandem duplicate 1; Belongs to the sterol desaturase family (271 aa)
     
  0.850
ENSLACG00000014870
Cholesterol 25-hydroxylase like 1, tandem duplicate 2; Belongs to the sterol desaturase family (293 aa)
     
  0.850
ENSLACG00000014587
Uncharacterized protein; Belongs to the cytochrome P450 family (513 aa)
     
  0.830
CYP7A1
Cytochrome P450, family 7, subfamily A, polypeptide 1 (514 aa)
     
  0.830
ENSLACG00000022525
annotation not available (555 aa)
   
  0.829
CYP27A1
Cytochrome P450, family 27, subfamily A, polypeptide 1 (539 aa)
   
  0.829
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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