Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Annotation not available (341 aa)
Predicted Functional Partners:
Fibrillarin (343 aa)
Histone cluster 1, H4a; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (103 aa)
KIAA0020 (641 aa)
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae) (524 aa)
Ribosomal protein S2 (290 aa)
WD repeat domain 43 (679 aa)
WD repeat domain 12 (339 aa)
GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (634 aa)
DDB1 and CUL4 associated factor 13 (472 aa)
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae) (345 aa)