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TP53INP1 protein (Latimeria chalumnae) - STRING interaction network
"TP53INP1" - Tumor protein p53 inducible nuclear protein 1 in Latimeria chalumnae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP53INP1Tumor protein p53 inducible nuclear protein 1 (240 aa)    
Predicted Functional Partners:
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family (401 aa)
       
 
  0.800
BLOC1S4
Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino (228 aa)
           
  0.646
CSRNP3
Cysteine-serine-rich nuclear protein 3 (523 aa)
           
  0.583
NUPR1
Nuclear protein, transcriptional regulator, 1 (93 aa)
           
  0.577
CDCA3
Uncharacterized protein; Cell division cycle associated 3 (351 aa)
           
  0.575
HIPK2
Homeodomain interacting protein kinase 2 (1188 aa)
       
 
  0.548
TBL3
Transducin (beta)-like 3 (803 aa)
           
  0.548
SEPT3
Uncharacterized protein; Septin 3; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Septin GTPase family (234 aa)
           
  0.542
GPR156
G protein-coupled receptor 156 (781 aa)
           
  0.533
EPCAM
Epithelial cell adhesion molecule (313 aa)
           
  0.525
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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