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APEX2 protein (Latimeria chalumnae) - STRING interaction network
"APEX2" - APEX nuclease (apurinic/apyrimidinic endonuclease) 2 in Latimeria chalumnae
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
APEX2APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (532 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (260 aa)
     
  0.897
NTHL1
Nth endonuclease III-like 1 (E. coli); Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N- glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines (350 aa)
     
  0.892
APTX
Aprataxin (372 aa)
     
 
  0.881
TDP1
tyrosyl-DNA phosphodiesterase 1 (614 aa)
     
 
  0.863
APEX1
APEX nuclease (multifunctional DNA repair enzyme) 1; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5’- deoxyribose phosphate and 3’-hydroxyl ends (314 aa)
   
 
0.857
PNKP
Polynucleotide kinase 3’-phosphatase (611 aa)
   
 
  0.851
MUTYH
mutY homolog (E. coli) (140 aa)
     
  0.843
NME8
NME/NM23 family member 8 (579 aa)
   
  0.786
ERCC4
Excision repair cross-complementing rodent repair deficiency, complementation group 4 (919 aa)
     
 
  0.775
FANCM
Fanconi anemia, complementation group M (2075 aa)
     
 
  0.764
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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