STRINGSTRING
ENSLACG00000000877 protein (Latimeria chalumnae) - STRING interaction network
"ENSLACG00000000877" - Uncharacterized protein in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSLACG00000000877Uncharacterized protein (364 aa)    
Predicted Functional Partners:
NODAL
Nodal homolog (mouse) (409 aa)
     
 
  0.908
ENSLACG00000008347
Uncharacterized protein (414 aa)
     
 
  0.908
ENSLACG00000017213
Uncharacterized protein (414 aa)
         
 
0.904
TGFB2
Transforming growth factor, beta 2 (415 aa)
         
 
0.904
TGFB3
Transforming growth factor, beta 3 (409 aa)
         
  0.903
TGFB1
Transforming growth factor, beta 1 (401 aa)
         
0.885
SMAD2
SMAD family member 2 (467 aa)
     
  0.692
ACVR2B
Activin A receptor, type IIB (515 aa)
       
  0.663
ACVR2A
Activin A receptor, type IIA (512 aa)
       
  0.663
ENSLACG00000010067
Transforming growth factor-beta receptor type II ; Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunos [...] (574 aa)
       
  0.659
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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