STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UACAUveal autoantigen with coiled-coil domains and ankyrin repeats. (1124 aa)    
Predicted Functional Partners:
FASTKD3
FAST kinase domains 3.
    
 0.676
RHOH
Ras homolog family member H.
    
  0.619
POLR3B
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.614
CASP9
Caspase 9; Belongs to the peptidase C14A family.
    
 0.608
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
      
 0.587
TOPORS
TOP1 binding arginine/serine rich protein.
    
 
 0.580
TMEM59
Transmembrane protein 59.
    
  0.566
APAF1
Apoptotic peptidase activating factor 1.
    
 0.554
MTR
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.543
PIAS2
Protein inhibitor of activated STAT 2.
    
 0.540
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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