STRINGSTRING
DAXX protein (Latimeria chalumnae) - STRING interaction network
"DAXX" - Death-domain associated protein in Latimeria chalumnae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DAXXDeath-domain associated protein (728 aa)    
Predicted Functional Partners:
ENSLACG00000001043
Annotation not available (136 aa)
     
 
  0.934
SUMO1
SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) (100 aa)
       
 
  0.918
MAP3K6
Mitogen-activated protein kinase kinase kinase 6 (1292 aa)
     
  0.914
MAP3K5
Mitogen-activated protein kinase kinase kinase 5 (1171 aa)
     
  0.914
FAS
Fas (TNF receptor superfamily, member 6) (330 aa)
     
  0.901
TGFBR2
Transforming growth factor, beta receptor II (70/80kDa); Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, i [...] (585 aa)
       
    0.812
ENSLACG00000010067
Transforming growth factor-beta receptor type II ; Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunos [...] (574 aa)
       
    0.810
TGFBR1
Transforming growth factor, beta receptor 1 (507 aa)
     
 
    0.800
HSPB1
Heat shock 27kDa protein 1 (219 aa)
       
 
  0.707
ATRX
Alpha thalassemia/mental retardation syndrome X-linked (2488 aa)
     
 
  0.660
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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