• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
ISCA1 protein (Latimeria chalumnae) - STRING interaction network
"ISCA1" - Iron-sulfur cluster assembly 1 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISCA1Iron-sulfur cluster assembly 1 (102 aa)    
Predicted Functional Partners:
FDX1L
Ferredoxin 1-like (182 aa)
   
 
  0.868
NFU1
NFU1 iron-sulfur cluster scaffold (253 aa)
   
 
  0.854
ISCU
Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron- sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins (170 aa)
   
   
  0.851
NFS1
NFS1 cysteine desulfurase; NFS1 nitrogen fixation 1 (S. cerevisiae) (449 aa)
   
   
  0.828
HSCB
HscB mitochondrial iron-sulfur cluster co-chaperone (257 aa)
   
 
  0.826
GLRX5
Glutaredoxin 5 homolog (S. cerevisiae) (157 aa)
   
 
  0.824
IBA57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) (314 aa)
   
 
  0.821
PSAT1
Phosphoserine aminotransferase 1 (368 aa)
           
  0.802
FDX1
Uncharacterized protein; Ferredoxin 1 (105 aa)
   
 
  0.792
LIAS
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (387 aa)
   
   
  0.787
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
Server load: low (10%) [HD]