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MEI1 protein (Latimeria chalumnae) - STRING interaction network
"MEI1" - Meiotic double-stranded break formation protein 1 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MEI1Meiotic double-stranded break formation protein 1; Meiosis inhibitor 1 (1147 aa)    
Predicted Functional Partners:
SYCE2
Synaptonemal complex central element protein 2 (130 aa)
     
   
  0.618
SPO11
SPO11, initiator of meiotic double stranded breaks; SPO11 meiotic protein covalently bound to DSB (394 aa)
           
  0.608
JMY
Junction mediating and regulatory protein, p53 cofactor (864 aa)
           
  0.583
SLC30A9
Solute carrier family 30 (zinc transporter), member 9 (561 aa)
           
  0.551
TEX12
Testis expressed 12 (124 aa)
           
  0.548
SYCP1
Synaptonemal complex protein 1 (925 aa)
           
  0.541
SDHD
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (156 aa)
           
  0.499
NAE1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M (536 aa)
           
  0.495
MEA1
Male-enhanced antigen 1 (185 aa)
           
  0.493
KATNB1
Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation (680 aa)
           
  0.491
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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