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EPAS1 protein (Latimeria chalumnae) - STRING interaction network
"EPAS1" - Endothelial PAS domain protein 1 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPAS1Endothelial PAS domain protein 1 (861 aa)    
Predicted Functional Partners:
ARNT
Aryl hydrocarbon receptor nuclear translocator (801 aa)
     
0.972
ENSLACG00000018618
Uncharacterized protein (205 aa)
       
  0.949
CREBBP
CREB binding protein (2411 aa)
     
  0.940
EGLN2
Egl nine homolog 2 (C. elegans) (444 aa)
       
  0.915
EGLN3
Egl nine homolog 3 (C. elegans) (241 aa)
     
  0.885
ARNT2
Aryl-hydrocarbon receptor nuclear translocator 2 (430 aa)
     
0.877
ENSLACG00000008756
Egl-9 family hypoxia-inducible factor 1 (129 aa)
       
  0.845
HIF1AN
Hypoxia inducible factor 1, alpha subunit inhibitor (347 aa)
       
  0.789
UBA52
Uncharacterized protein (128 aa)
       
  0.737
ENSLACG00000008149
Uncharacterized protein (949 aa)
     
  0.719
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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