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ADRB3 protein (Latimeria chalumnae) - STRING interaction network
"ADRB3" - Adrenergic receptor, beta 3b in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADRB3Adrenergic receptor, beta 3b (407 aa)    
Predicted Functional Partners:
GNAL
Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (379 aa)
       
  0.844
GNAS
GNAS complex locus (377 aa)
       
  0.834
ADRB1
Adrenoceptor beta 1 (394 aa)
       
0.828
TAF5
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa (622 aa)
     
 
  0.804
NPY
Neuropeptide Y (100 aa)
       
 
  0.674
BHLHE22
Basic helix-loop-helix family, member e22 (270 aa)
       
 
  0.660
GNB3
G protein subunit beta 3; Guanine nucleotide binding protein (G protein), beta polypeptide 3 (341 aa)
       
 
  0.627
PPARG
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (403 aa)
           
  0.626
ENSLACG00000006484
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (111 aa)
           
  0.583
DUSP26
Dual specificity phosphatase 26 (putative); Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily (196 aa)
           
  0.548
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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