STRINGSTRING
CRH protein (Latimeria chalumnae) - STRING interaction network
"CRH" - Corticotropin releasing hormone in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRHCorticotropin releasing hormone (166 aa)    
Predicted Functional Partners:
POMC
Proopiomelanocortin (255 aa)
     
 
  0.895
CRHR1
Corticotropin releasing hormone receptor 1 (376 aa)
     
  0.855
CRHR2
Corticotropin releasing hormone receptor 2 (270 aa)
     
  0.839
CGA
Glycoprotein hormones, alpha polypeptide (120 aa)
     
 
  0.754
ADCYAP1
Adenylate cyclase activating polypeptide 1 (pituitary) (199 aa)
     
 
  0.726
CRHBP
Corticotropin releasing hormone binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy (323 aa)
     
   
  0.726
GHRH
Growth hormone releasing hormone (168 aa)
         
  0.711
MC4R
Melanocortin 4 receptor (329 aa)
     
 
  0.673
FOS
FBJ murine osteosarcoma viral oncogene homolog (391 aa)
           
  0.668
VIP
Vasoactive intestinal peptide (205 aa)
     
 
  0.664
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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