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STRINGSTRING
ERCC6L protein (Latimeria chalumnae) - STRING interaction network
"ERCC6L" - ERCC excision repair 6 like, spindle assembly checkpoint helicase in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase; Excision repair cross-complementing rodent repair deficiency, complementation group 6-like (1224 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK; Polo-like kinase 1 (595 aa)
     
 
  0.954
RMI1
RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae) (616 aa)
     
 
  0.945
TOP3A
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (999 aa)
   
 
  0.924
BEND3
BEN domain containing 3 (842 aa)
     
 
  0.913
BLM
Bloom syndrome, RecQ helicase-like (1450 aa)
   
 
  0.889
NCAPG
non-SMC condensin I complex, subunit G (1067 aa)
     
   
  0.806
POLR2I
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (125 aa)
       
 
  0.788
ERCC5
ERCC excision repair 5, endonuclease; Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome)) (1193 aa)
     
 
  0.786
PLK2
Serine/threonine-protein kinase PLK; Polo-like kinase 2 (731 aa)
     
 
  0.763
FANCM
Fanconi anemia, complementation group M (2075 aa)
     
 
  0.749
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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