STRINGSTRING
IFNAR1 protein (Latimeria chalumnae) - STRING interaction network
"IFNAR1" - Interferon (alpha, beta and omega) receptor 1 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IFNAR1Interferon (alpha, beta and omega) receptor 1 (548 aa)    
Predicted Functional Partners:
JAK1
Janus kinase 1 (613 aa)
     
  0.979
STAT2
Signal transducer and activator of transcription 2, 113kDa (765 aa)
     
  0.948
JAK3
Janus kinase 3 (1116 aa)
     
  0.940
JAK2
Janus kinase 2 (1152 aa)
     
  0.940
STAT1
Signal transducer and activator of transcription 1, 91kDa (1179 aa)
     
  0.934
ENSLACG00000003191
Uncharacterized protein (170 aa)
       
  0.865
IL6
Interleukin 6 (interferon, beta 2) (149 aa)
         
  0.835
IL10
Interleukin 10 (185 aa)
         
  0.821
IL12B
Interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated killer cells, and stimulate the production of IFN-gamma by resting PBMC (329 aa)
         
  0.810
IL22
Interleukin 22 (188 aa)
         
  0.807
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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