STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TAPT1Transmembrane anterior posterior transformation 1. (597 aa)    
Predicted Functional Partners:
CSTF1
Cleavage stimulation factor subunit 1.
 
      0.810
SUCO
SUN domain containing ossification factor.
    
   0.779
LEP
Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.
      
 0.618
ZFYVE1
Zinc finger FYVE-type containing 1.
   
    0.582
ESF1
ESF1 nucleolar pre-rRNA processing protein homolog.
      
 0.572
LOC102348329
Secreted phosphoprotein 2.
   
  
 0.565
HAUS3
HAUS augmin like complex subunit 3.
      
 0.549
LAP3
Leucine aminopeptidase 3.
      
 0.544
H3ACE0_LATCH
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
      
 0.543
LOC102357932
Si:ch211-11n16.2.
   
    0.530
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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