STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RFX3Regulatory factor X3. (639 aa)    
Predicted Functional Partners:
LOC106703151
Uncharacterized protein.
 
      0.892
ATR
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
 
 0.825
DPCD
Deleted in primary ciliary dyskinesia homolog (mouse).
      
 0.593
CHEK2
Checkpoint kinase 2.
   
 
 0.590
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4.
    
 
 0.546
RFXAP
Regulatory factor X associated protein.
    
 
 0.528
BTF3L4
Transcription factor BTF3; Belongs to the NAC-beta family.
      
 0.507
SPEF2
Sperm flagellar 2.
    
 
 0.504
SPAG6
Sperm associated antigen 6.
      
 0.465
E2F2
E2F transcription factor 2.
      
 0.448
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.