STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STAT3Signal transducer and activator of transcription. (763 aa)    
Predicted Functional Partners:
LOC102352539
Uncharacterized protein.
    
 0.975
JAK2
Tyrosine-protein kinase.
   
 0.953
LOC102348150
Signal transducer and activator of transcription.
   
0.941
IL6
Uncharacterized protein.
   
 0.933
SOCS3
Suppressor of cytokine signaling 3.
   
 0.922
JAK1
Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.915
CREBBP
CREB binding protein.
    
 0.912
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 0.888
LOC102360670
Uncharacterized protein.
   
 0.882
SRC
Tyrosine-protein kinase.
   
 0.881
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.