STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRIP1BRCA1 interacting protein C-terminal helicase 1. (716 aa)    
Predicted Functional Partners:
TOPBP1
DNA topoisomerase II binding protein 1.
   
 0.994
SLF1
SMC5-SMC6 complex localization factor 1.
   
 0.992
H2ZWI5_LATCH
Uncharacterized protein.
  
 0.990
PMS2
PMS1 homolog 2, mismatch repair system component.
   
 0.961
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
   
 0.938
BARD1
BRCA1 associated RING domain 1.
   
 0.938
GTF2H1
General transcription factor IIH subunit 1.
    
 0.935
LOC102353559
General transcription factor IIH subunit.
    
 0.933
BRCA1
BRCA1 DNA repair associated.
   
 0.932
GTF2H3
General transcription factor IIH subunit 3.
    
 0.931
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.