STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR11WD repeat domain 11. (1258 aa)    
Predicted Functional Partners:
POLL
DNA polymerase lambda; Belongs to the DNA polymerase type-X family.
      
 0.865
FAM91A1
Family with sequence similarity 91 member A1.
     
 0.775
C17orf75
Chromosome 17 open reading frame 75.
    
 
 0.700
TRAPPC11
Trafficking protein particle complex 11.
   
    0.675
NAA40
N(alpha)-acetyltransferase 40, NatD catalytic subunit.
    
   0.648
ANKRD50
Ankyrin repeat domain 50.
     
 0.643
MTR
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.624
RHOH
Ras homolog family member H.
    
  0.596
AUP1
AUP1 lipid droplet regulating VLDL assembly factor.
      
 0.581
ADGRA3
Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family.
      
 0.570
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.