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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa)    
Predicted Functional Partners:
AEH22727.1
PFAM: Phosphate transporter; KEGG: tye:THEYE_A1362 sodium/phosphate symporter.
       0.732
AEH22728.1
Protein of unknown function DUF47; KEGG: tye:THEYE_A1361 hypothetical protein; TIGRFAM: Protein of unknown function DUF47; PFAM: Putitive phosphate transport regulator.
       0.732
AEH22729.1
Putative signal transduction protein with CBS domains; KEGG: tye:THEYE_A1360 CBS domain protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
  
    0.720
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.706
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.670
AEH23336.1
KEGG: hth:HTH_0871 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal.
     
 0.576
AEH22730.1
PFAM: Inositol monophosphatase; NUDIX hydrolase domain; KEGG: dak:DaAHT2_0139 inositol monophosphatase.
     
 0.548
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.530
AEH23620.1
KEGG: sep:SE1274 ComEC late competence protein 3; TIGRFAM: Competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein.
     
 0.530
AEH22731.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; KEGG: dak:DaAHT2_1538 response regulator receiver modulated diguanylate cyclase; SMART: Diguanylate cyclase, predicted.
       0.502
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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