STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK18Si:dkey-166c18.1; Belongs to the protein kinase superfamily. (465 aa)    
Predicted Functional Partners:
ccnb2
Cyclin B2; Belongs to the cyclin family.
   
 
 0.723
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 
 0.698
ccnb1
Cyclin B1; Belongs to the cyclin family.
   
 
 0.694
ccne2
Cyclin E2; Belongs to the cyclin family.
   
 
 0.683
cks2
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 
 0.674
ccna1
Cyclin A1; Belongs to the cyclin family.
   
 
 0.671
ccna2
Cyclin A2; Belongs to the cyclin family.
   
 
 0.671
ablim3
Actin-binding LIM protein family, member 3.
      
 0.669
cdc25b
Cell division cycle 25B.
   
 
 0.666
ccng1
Cyclin G1; Belongs to the cyclin family.
   
 
 0.663
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.