STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ugdhUDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (493 aa)    
Predicted Functional Partners:
uxs1
UDP-glucuronic acid decarboxylase 1; Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis (By similarity). Essential during embryogenesis for craniofacial development. Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
 0.999
gale
UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
 
 0.985
ugp2a
UTP--glucose-1-phosphate uridylyltransferase.
     
 0.979
ugp2b
UTP--glucose-1-phosphate uridylyltransferase.
   
 
 0.964
galt
Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
    
 0.884
has2
Hyaluronan synthase 2.
  
 
 0.871
chsy1
Hexosyltransferase.
      
 0.857
has3
Hyaluronan synthase 3.
  
 
 0.846
gkup
Glucuronokinase with putative uridyl pyrophosphorylase.
     
 0.819
nsdhl
NAD(P)-dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
  
 0.796
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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